The Burden of Urinary Tract Infections on Quality of Life and Healthcare in Patients with Interstitial Cystitis (2024)

Baars, C., van Ginkel, C., Heesakkers, J., Scholtes, M., Martens, F., & Janssen, D. (2023). The Burden of Urinary Tract Infections on Quality of Life and Healthcare in Patients with Interstitial Cystitis. Healthcare, 11(20), Article 2761. https://doi.org/10.3390/healthcare11202761

Baars, Cléo ; van Ginkel, Charlotte ; Heesakkers, John et al. / The Burden of Urinary Tract Infections on Quality of Life and Healthcare in Patients with Interstitial Cystitis. In: Healthcare. 2023 ; Vol. 11, No. 20.

@article{4252fe0b27e242799ae50fad405b4f56,

title = "The Burden of Urinary Tract Infections on Quality of Life and Healthcare in Patients with Interstitial Cystitis",

abstract = "Background: Interstitial cystitis/bladder pain syndrome (IC/BPS) patients are more susceptible to urinary tract infections (UTIs), likely worsening pre-existing symptoms. However, this receives limited attention in guidelines. This study aimed to explore the burden of UTIs on IC/BPS patients{\textquoteright} quality of life and their healthcare. Methods: Two quantitative retrospective database studies were conducted in cystoscopically proven IC/BPS patients: one compiled existing patient survey data (n = 217) from July 2021 to examine physical and emotional UTI burden, and the other used a patient file database (n = 100) from January 2020 to May 2022, focusing on UTI prevalence, healthcare use, urine cultures and antibiotic resistance. Results: A delay in diagnosis was seen in 70% of patients, due to doctors confusing IC/BPS symptoms with UTIs. The UTI prevalence was over 50%; these patients also report anxiety for new UTIs (70%) and worsening of IC/BPS symptoms (60%). Additionally, for UTI+ patients, healthcare consumption was significantly increased in both studies. Antibiotic resistance (80% of cultures) and prophylactic antibiotic use were common. Conclusions: These findings highlight the burden of UTIs on quality of life in IC/BPS patients and the healthcare system. These results emphasize the need for improved UTI guidelines concerning diagnosis, management and prevention for IC/BPS patients to improve quality of life and care.",

keywords = "bladder pain syndrome, burden of illness, healthcare surveys, interstitial cystitis, quality of life, urinary tract infections",

author = "Cl{\'e}o Baars and {van Ginkel}, Charlotte and John Heesakkers and Mathilde Scholtes and Frank Martens and Dick Janssen",

note = "Publisher Copyright: {\textcopyright} 2023 by the authors.",

year = "2023",

month = oct,

day = "1",

doi = "10.3390/healthcare11202761",

language = "English",

volume = "11",

journal = "Healthcare",

issn = "2227-9032",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "20",

}

Baars, C, van Ginkel, C, Heesakkers, J, Scholtes, M, Martens, F & Janssen, D 2023, 'The Burden of Urinary Tract Infections on Quality of Life and Healthcare in Patients with Interstitial Cystitis', Healthcare, vol. 11, no. 20, 2761. https://doi.org/10.3390/healthcare11202761

The Burden of Urinary Tract Infections on Quality of Life and Healthcare in Patients with Interstitial Cystitis. / Baars, Cléo; van Ginkel, Charlotte; Heesakkers, John et al.
In: Healthcare, Vol. 11, No. 20, 2761, 01.10.2023.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - The Burden of Urinary Tract Infections on Quality of Life and Healthcare in Patients with Interstitial Cystitis

AU - Baars, Cléo

AU - van Ginkel, Charlotte

AU - Heesakkers, John

AU - Scholtes, Mathilde

AU - Martens, Frank

AU - Janssen, Dick

N1 - Publisher Copyright:© 2023 by the authors.

PY - 2023/10/1

Y1 - 2023/10/1

N2 - Background: Interstitial cystitis/bladder pain syndrome (IC/BPS) patients are more susceptible to urinary tract infections (UTIs), likely worsening pre-existing symptoms. However, this receives limited attention in guidelines. This study aimed to explore the burden of UTIs on IC/BPS patients’ quality of life and their healthcare. Methods: Two quantitative retrospective database studies were conducted in cystoscopically proven IC/BPS patients: one compiled existing patient survey data (n = 217) from July 2021 to examine physical and emotional UTI burden, and the other used a patient file database (n = 100) from January 2020 to May 2022, focusing on UTI prevalence, healthcare use, urine cultures and antibiotic resistance. Results: A delay in diagnosis was seen in 70% of patients, due to doctors confusing IC/BPS symptoms with UTIs. The UTI prevalence was over 50%; these patients also report anxiety for new UTIs (70%) and worsening of IC/BPS symptoms (60%). Additionally, for UTI+ patients, healthcare consumption was significantly increased in both studies. Antibiotic resistance (80% of cultures) and prophylactic antibiotic use were common. Conclusions: These findings highlight the burden of UTIs on quality of life in IC/BPS patients and the healthcare system. These results emphasize the need for improved UTI guidelines concerning diagnosis, management and prevention for IC/BPS patients to improve quality of life and care.

AB - Background: Interstitial cystitis/bladder pain syndrome (IC/BPS) patients are more susceptible to urinary tract infections (UTIs), likely worsening pre-existing symptoms. However, this receives limited attention in guidelines. This study aimed to explore the burden of UTIs on IC/BPS patients’ quality of life and their healthcare. Methods: Two quantitative retrospective database studies were conducted in cystoscopically proven IC/BPS patients: one compiled existing patient survey data (n = 217) from July 2021 to examine physical and emotional UTI burden, and the other used a patient file database (n = 100) from January 2020 to May 2022, focusing on UTI prevalence, healthcare use, urine cultures and antibiotic resistance. Results: A delay in diagnosis was seen in 70% of patients, due to doctors confusing IC/BPS symptoms with UTIs. The UTI prevalence was over 50%; these patients also report anxiety for new UTIs (70%) and worsening of IC/BPS symptoms (60%). Additionally, for UTI+ patients, healthcare consumption was significantly increased in both studies. Antibiotic resistance (80% of cultures) and prophylactic antibiotic use were common. Conclusions: These findings highlight the burden of UTIs on quality of life in IC/BPS patients and the healthcare system. These results emphasize the need for improved UTI guidelines concerning diagnosis, management and prevention for IC/BPS patients to improve quality of life and care.

KW - bladder pain syndrome

KW - burden of illness

KW - healthcare surveys

KW - interstitial cystitis

KW - quality of life

KW - urinary tract infections

U2 - 10.3390/healthcare11202761

DO - 10.3390/healthcare11202761

M3 - Article

SN - 2227-9032

VL - 11

JO - Healthcare

JF - Healthcare

IS - 20

M1 - 2761

ER -

Baars C, van Ginkel C, Heesakkers J, Scholtes M, Martens F, Janssen D. The Burden of Urinary Tract Infections on Quality of Life and Healthcare in Patients with Interstitial Cystitis. Healthcare. 2023 Oct 1;11(20):2761. doi: 10.3390/healthcare11202761