What is Glucose-Fructose Syrup? (Q&A) (2024)

Last Updated : 05 April 2018

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    Glucose-fructose syrup is a sweetening ingredient widely used in a variety of food products. Read our Q&As for more information about it, how it is made and its impact on our health.

    What are glucose and fructose?

    Glucose is a simple sugar, a so-called monosaccharide, because it is made up of just one sugar unit. It is found naturally in many foods, and it is used by our bodies as a source of energy to carry out daily activities.

    Fructose is also a simple sugar, often referred to as a fruit sugar. Fructose, as the name suggest, is found in fruits (such as oranges and apples), berries, some root vegetables(such as beets, sweet potatoes, parsnips, and onions) and honey. Fructose is the sweetest of all naturally occurring sugars.

    Glucose and fructose bound together in equal amounts create another type of sugar – sucrose – a disaccharide commonly known as table sugar.

    What is Glucose-Fructose Syrup (GFS)?

    GFS is a sweet liquid made of glucose and fructose. Unlike sucrose, where 50% of glucose and 50% of fructose are linked together, GFS can have a varying ratio of the two simple sugars, meaning that some extra, unbound glucose or fructose molecules are present. The fructose content in GFS can range from 5% to over 50%.

    How is GFS made?

    GFS is typically made from starch. The source of starch depends on the local availability of the raw product used for extraction. Historically, maize was a preferred choice, while in recent years wheat became a popular source for the GFS production. Starch is a chain of glucose molecules, and the first step in GFS production involves freeing those glucose units. The linked glucose molecules in starch are cut down (hydrolysed) into free glucose molecules. Then, with the use of enzymes, some of the glucose is changed into fructose in a process called isomerisation.

    Check our infographic on how GFS is produced

    What is GFS used for?

    The main reasons for using GFS in foods and drinks are its sweetness and the ability to blend nicely with other ingredients. Interestingly, it can be also used in place of additives for food preservation (an effect also observed with table sugar). This helps to fulfil the needs of consumers when they desire products without additives. Apart from better stability, GFS can also improve the texture, prevent crystallisation, and help to achieve desired consistency (crispy versus moist).

    Are GFS, Isoglucose and High Fructose Corn Syrup (HFCS) the same thing?

    There is a lot of confusion around the terms glucose-fructose syrup, isoglucose and high fructose corn syrup which are often used interchangeably.

    GFS may be called differently depending on the country and the fructose content. In Europe, due to ‘isomerisation’ process, GFS with more than 10% fructose is called isoglucose. In turn, when the fructose content exceeds 50%, the name changes to Fructose-Glucose Syrup to reflect the higher content of fructose.

    In the United States, the syrup is produced from a maize starch, usually with either 42% or 55% fructose content, hence it is called High Fructose Corn Syrup.

    Is GFS used in many food products?

    In Europe, sucrose is still the main caloric sweetener used in the production of food and drinks. The production of GFS in the EU was regulated by the European Sugar Regime and was limited to 5% of total sugar production. However, in October 2017 the regime ended, and the production of GFS is estimated to increase from 0,7 to 2,3 million tonnes a year. As a consequence, in the future, GFS may replace sucrose in certain products, mainly in liquid or semi-solid foods, such as drinks and ice cream. It will continue being used for confectionery, jams and preserves, baked goods, cereal products, dairy products, condiments and canned and packed goods.

    In the US, GFS (or HFCS) is more commonly used than in Europe, typically in soft drinks where the HFCS with fructose content of at least 42% is used.

    What is the nutritional value of GFS?

    GFS is a source of carbohydrates, which along with proteins and fats are the foundation of our diet. The human body uses them for energy, development and maintenance. GFS is nutritionally equivalent to other carbohydrates, containing the same number of 4 kcal per gram, and has the health impact of added sugars.

    How much GFS is OK to use?

    In 2010, the European Food Safety Authority’s Panel on Dietetic Products, Nutrition and Allergies (EFSA NDA Panel) published a scientific opinion on dietary reference values for the intake of carbohydrates and sugars. They advised that the intake of total carbohydrates - including carbohydrates from starchy foods such as potatoes and pasta, and from simple carbohydrates such as sugars - should range from 45 to 60% of the total energy intake for both adults and children older than one year of age. However, the Panel found insufficient evidence to set an upper limit for added sugars intake.

    In 2015, the WHO published a guideline advising people to reduce their daily intake of added sugars to less than 10% of total energy intake. For an active adult requiring 2000 kcal a day, this equates to less than 200 kcal from free sugars, which is about 50 grams, or 12 teaspoons of sugar. According to WHO, evidence shows that such reduction reduces the risk of overweight, obesity and tooth decay.

    Is there a link between GFS consumption and obesity?

    Many factors contribute to the development of obesity. Nutritionists, health experts and researchers generally agree that the main cause is an imbalance between calories consumed and calories burned. Excessive calories can be consumed as fats, proteins, alcohol or carbohydrates, including sugars.

    Some reports have suggested that excess consumption of GFS may be responsible for the current obesity crisis in the U.S. However, obesity rates have also risen dramatically across Europe in the absence of a parallel rise in GFS intakes, making it implausible that the increased incidence of obesity is caused by GFS only.

    How about fructose, is it good or bad for our health?

    In the past, a role of fructose in the development of obesity and metabolic diseases has been proposed. This hypothesis was based on either animal studies or human trials with very high fructose intake (>20% of daily energy needs). Such consumption of fructose as the sole carbohydrate is highly unusual, not at all reflecting people’s daily diets. Research on fructose when consumed in usual amounts by most people remains inconclusive, however, and does not show a direct effect of fructose on metabolic diseases or obesity.

    Does fructose affect the feelings of fullness?

    Some studies attempted to show that fructose may not be as satiating (producing a feeling of fullness) as other sugars, because it does not stimulate the hormones responsible for hunger and food intake (such as insulin). This could cause people to eat or drink more. However, a review from 2007 concluded that the evidence for fructose being less satiating than glucose, or GFS being less satiating than sucrose, is not compelling. Since then, research has shown that glucose and fructose have the same effect on satiety and fullness as observed in people consuming beverages sweetened either with glucose, fructose or HFCS.

    Does the European Food Safety Authority (EFSA) have an opinion on fructose and satiety?

    At present, the European Food Safety Authority (EFSA) has not made a statement concerning fructose and satiety. EFSA will provide scientific advice on the daily intake of added sugar in food by early 2020.

    What is Glucose-Fructose Syrup? (Q&A) (2024)

    FAQs

    What is glucose or fructose syrup? ›

    While table sugar has a fixed proportion of 50% glucose and 50% fructose, the percentage of these molecules in syrups may vary. If a syrup contains more than 50% of fructose, it is called “fructose-glucose syrup” on the packaging. If there is less than 50% fructose in it, it is called “glucose-fructose syrup”.

    What is glucose-fructose syrup made of? ›

    Glucose-fructose syrup* is a plant-based sugar, made from grains. EU starch manufacturers only use conventional (non- GMO) wheat and maize which are almost exclusively domestically produced. Unlike glucose syrup which contains no fructose, glucose-fructose syrup is made up of two simple sugars: glucose and fructose.

    What does glucose-fructose syrup do? ›

    What is GFS used for? The main reasons for using GFS in foods and drinks are its sweetness and the ability to blend nicely with other ingredients. Interestingly, it can be also used in place of additives for food preservation (an effect also observed with table sugar).

    Is glucose-fructose syrup worse than sugar? ›

    High-fructose corn syrup isn't necessarily worse for us than table sugar, but there is just too much of it in our food supply, says Harvard School of Public Health nutrition expert Frank Hu.

    What is the main difference between glucose and fructose? ›

    Fructose changes blood sugar levels much more gradually than glucose and doesn't seem to impact insulin levels. Unlike glucose, which is processed throughout the whole body, fructose is almost entirely metabolized by the liver. Over time, overconsumption can cause fatty liver and visceral fat around essential organs.

    What type of sugar is glucose and fructose? ›

    Carbohydrates are classified into two subtypes of sugar: monosaccharides, or "simple sugars" (consisting of one molecule) and disaccharides (two molecules). The monosaccharides include glucose, fructose, and galactose.

    Is glucose syrup as bad as high-fructose corn syrup? ›

    A study found no differences in the consumption of fructose versus high-fructose corn syrup versus glucose. Consumption of sugar-sweetened beverages (SSBs) has been associated with increased risk of heart disease, type 2 diabetes, and metabolic syndrome.

    Is glucose-fructose syrup a corn syrup? ›

    High-fructose corn syrup (HFCS), also known as glucose–fructose, isoglucose and glucose–fructose syrup, is a sweetener made from corn starch. As in the production of conventional corn syrup, the starch is broken down into glucose by enzymes.

    Is glucose-fructose syrup natural? ›

    Glucose-fructose syrup is a natural sugar found in honey, fruits and some root vegetables.

    Is glucose fructose safe? ›

    Excessive fructose consumption, while not always affecting your blood glucose levels, has been linked to weight gain, increased risk of obesity, and insulin resistance. Because of these associations, consuming high amounts of fructose can contribute to impaired glucose and other risk factors of metabolic syndrome.

    Is glucose-fructose syrup harmful? ›

    Added sugars and high fructose corn syrup are considered primary causes of the overweighting of America. Weight gain abetted by high-calorie foods containing HFCS can also contribute to heart disease, diabetes, fatty liver disease and dyslipidemia, an abnormal level of cholesterol and other fats in the blood.

    Why is glucose fructose bad? ›

    Ingestion of fructose chronically has contributed to multiple health consequences, such as insulin resistance, obesity, liver disorders, and diabetes. Fructose metabolism starts with fructose phosphorylation by fructose kinase in the liver, and this process is not feedback regulated.

    What is the unhealthiest sugar? ›

    Glucose and fructose are simple sugars, or monosaccharides. Your body can absorb them more easily than the disaccharide sucrose, which must be broken down first. Added fructose may have the most negative health effects, but experts agree that you should limit your intake of all types of added sugar.

    What is the healthiest type of sugar? ›

    Talking about sugar being good for health, then natural sugar or stevia is the best. They have many health benefits to offer apart from weight loss. It has all the essential nutrients, vitamins, and minerals that are essential for your body. While stevia is also known to be the best sugar for weight loss.

    Is glucose fructose an artificial sweetener? ›

    Glucose and fructose are natural sugars, and are found in fruits and vegetables. On the other hand, artificial sweeteners are sugars that are chemically modified in a lab and provide sweetening typically without calories.

    Is honey a glucose or fructose? ›

    Honey is approximately 40% fructose, 30% glucose and 17% water, with the remainder being other sugars, carbohydrates and a small amount of vitamins and minerals.

    Is honey a fructose? ›

    Fructose content of honey varies from 21 to 43% and the fructose/glucose ratio from 0.4 to 1.6 or even higher [31–34]. Although fructose is the sweetest naturally occurring sweetener, it has a glycemic index of 19, compared to glucose which has 100 or sucrose (refined sugar) with 60 [35].

    Does the body prefer glucose or fructose? ›

    Glucose is the preferred energy source for the body, especially the brain and muscles, whereas fructose is not the most preferred energy source. Glucose is less fat-producing as compared to fructose. Glucose metabolism in the body is much slower than fructose.

    What are the 4 types of sugar? ›

    We look at fructose, glucose, lactose and sucrose. You've probably heard the terms fructose, glucose, lactose and sucrose before, and you may know that they're all types of sugar.

    Which fruit are high in fructose? ›

    People who have fructose intolerance should limit high-fructose foods, such as juices, apples, grapes, watermelon, asparagus, peas and zucchini. Some lower fructose foods — such as bananas, blueberries, strawberries, carrots, avocados, green beans and lettuce — may be tolerated in limited quantities with meals.

    Is there a healthy sugar? ›

    Sweeteners like fruit juice, honey, molasses and maple syrup contain natural sugar and have some nutritional benefits. Fruit has fiber, vitamins and antioxidants. Even raw honey and maple syrup can contain antioxidants and minerals like iron, zinc, calcium and potassium.

    Is Karo syrup the same as glucose syrup? ›

    So, the corn syrup you see in bottles in the grocery store is just plain, glucose syrup, sold most often by Karo, the largest national brand.

    Is glucose syrup safe for diabetics? ›

    Glucose is used to treat very low blood sugar (hypoglycemia), most often in people with diabetes mellitus. glucose works by quickly increasing the amount of glucose in your blood. Glucose is also used to provide carbohydrate calories to a person who cannot eat because of illness, trauma, or other medical condition.

    Why is high fructose worse than sugar? ›

    There is currently no evidence to suggest that HFCS is any worse than sugar. Both high fructose corn syrup and sugar are essentially the same; the difference between them is too small to matter in moderate consumption, and in excess both are harmful to health.

    Is glucose syrup worse than sugar? ›

    One tablespoon (15 ml) is loaded with 62 calories and 17 grams of carbs — nearly 4 times more than the amounts found in table sugar ( 8 , 9 ). Consuming glucose syrup regularly may increase your risk of obesity, high blood sugar, poor dental health, high blood pressure, and heart disease ( 10 , 11 ).

    What is the difference between sugar and glucose syrup? ›

    Glucose syrup is a refined and concentrated solution of dextrose, maltose and higher saccharides, obtained by hydrolysis of starch. It is more distinct than sugar, partly because it is a syrup, which means that the solution is a thick, sweetish liquid.

    Is glucose syrup from wheat or corn? ›

    Glucose syrups are typically made from a non-gluten source such as maize (corn) and less commonly from rice and potato. A Gluten Free label on a product overrides the ingredient list – it contains no-detectable gluten.

    Is sugar glucose fructose the same as high fructose corn syrup? ›

    Glucose and fructose are linked in sugar as a disaccharide, whereas HFCS consists of a mixture of free glucose and fructose molecules. Since sugar is broken down into glucose and fructose by enzymes in the small intestine, HFCS and sugar are essentially equivalent after being absorbed by the body.

    What countries have banned high fructose corn syrup? ›

    The countries where no HFCS at all is used include India, Ireland, Sweden, Austria, Uruguay, and Lithuania. France, China, Australia, and the UK all use less than one pound per capita.

    What is the new name for high fructose corn syrup? ›

    Well, the Corn Refiners Association (CRA) argue that they have simply changed a form of HFCS called HFCS-90 (90% pure fructose) to be called fructose or fructose syrup. Manufacturers argue that fructose isn't as bad because fructose makes up the sugar content in fruits.

    Who should avoid fructose? ›

    Why do I Need to Follow a Low-Fructose Diet? Fructose intolerance can occur in people with irritable bowel syndrome (IBS) and other GI disorders. In some individuals, fructose is not digested or absorbed well in the body, causing bloating, abdominal pain, nausea, gas, and diarrhea.

    Is fructose the worst type of sugar? ›

    Excessive fructose, just like too much of any added sugars, is not healthy. Fructose is converted to glucose in the liver, but if there's too much, the liver produces uric acid and fat in the form of triglycerides. This, in turn, may increase the risk of fatty liver disease, gout, and heart disease.

    Does fructose cause inflammation? ›

    The researchers found that fructose causes the immune system to become inflamed. This process, in turn, produces more reactive molecules, which are associated with inflammation. Specifically, this sugar adjusts cellular metabolic pathways to promote the production of more reactive inflammatory cytokines.

    Is it bad to eat glucose syrup? ›

    Answer. Glucose syrup is considered safe even when derived from wheat, barley or rye. That is because the process used to produce glucose syrup renders the starting material to contain less than 20 parts per million of gluten, which is considered a safe concentration for those with celiac disease.

    How much fructose is safe per day? ›

    “According to analysis of clinical trials evaluating fructose intake, 25-40g of fructose per day is totally safe. “However if you have fructose malabsorption you need to keep your fructose intake to less than 25g a day.

    How long does fructose stay in your body? ›

    How long does fructose stay in your system? Normally, fructose is metabolized within six hours after it's consumed. However, it could stay in your system for a few days or weeks if you have fructose intolerance.

    How much fructose is unhealthy? ›

    A meta-analysis found that individuals had to consume >100 grams of fructose per day to see adverse effects on body fat or metabolic markers. To summarize this, it appears that for most of us, fructose intake between 0 and ~80-90 grams per day does not convey a substantial health risk.

    What kind of sugar is OK? ›

    Natural sugars are safe to eat

    Any sugar that is naturally occurring in a food gets the green light. That includes sugar in fruit and starchy vegetables, as well as whole or minimally processed carbohydrates like brown rice and whole grain pasta. Sugar in dairy products like milk and cheese is OK, too.

    What sweeteners should you avoid? ›

    The worst sweeteners include artificial sweeteners like sucralose, saccharin, and aspartame, high fructose corn syrup, agave, and brown rice syrup. It's best to avoid these sweeteners, if possible.

    What organ is sugar the worst for? ›

    When you consume sugar, your pancreas must produce insulin to normalize your blood sugar levels. Overconsumption of sugar will cause your pancreas to work overtime and get damaged.

    Which is healthier sugar or honey? ›

    From a calorie and sugar content perspective, the differences between sugar and honey are minimal, however, overall, honey contains slightly more health benefits than table sugar from its potential antioxidant, antibacterial, antifungal, and anti-inflammatory properties.

    Is there anything better than sugar? ›

    Stevia, monk fruit, certain sugar alcohols, and allulose are much lower in calories than table sugar and do not significantly affect blood sugar levels, making them a smart alternative to refined sugar.

    Is brown sugar OK? ›

    Because of its molasses content, brown sugar does contain certain minerals, most notably calcium, potassium, iron and magnesium (white sugar contains none of these). But since these minerals are present in only minuscule amounts, there is no real health benefit to using brown sugar.

    What sweetener is in co*ke Zero? ›

    One liter of Coca-Cola Zero Sugar contains 96 mg caffeine. Additionally, artificial sweeteners are used. In the U.S., this includes aspartame and acesulfame potassium. However, the exact combination of sweeteners and preservatives used varies from market to market.

    What's the fake sugar called? ›

    Common artificial sweeteners include: Aspartame. Sucralose. Acesulfame K.

    What is the most common fake sugar? ›

    Aspartame Aspartame (also known as Equal) is one of the most popular artificial sweeteners, adding sweetness to diet sodas, desserts, cereals, and many other foods and beverages.

    Which is healthier fructose or glucose? ›

    The new study — drawing on clinical trials, basic science, and animal studies — concludes that fructose is more damaging to health than glucose. Lucan and DiNicolantonio lay out a series of findings that show the digestive tract doesn't absorb fructose as well as other sugars. More fructose then goes into the liver.

    Is glucose-fructose syrup bad for you? ›

    Added sugars and high fructose corn syrup are considered primary causes of the overweighting of America. Weight gain abetted by high-calorie foods containing HFCS can also contribute to heart disease, diabetes, fatty liver disease and dyslipidemia, an abnormal level of cholesterol and other fats in the blood.

    Is glucose syrup bad for you? ›

    Glucose syrup is a liquid sweetener often used in commercial foods to improve taste and shelf life. However, eating this syrup regularly is unhealthy, as it's highly processed and loaded with calories and sugar. As such, it's best to avoid this ingredient. Instead, look for foods that contain healthier sweeteners.

    Which is worse glucose syrup or high fructose corn syrup? ›

    A study found no differences in the consumption of fructose versus high-fructose corn syrup versus glucose. Consumption of sugar-sweetened beverages (SSBs) has been associated with increased risk of heart disease, type 2 diabetes, and metabolic syndrome.

    Which is the healthiest sugar? ›

    Talking about sugar being good for health, then natural sugar or stevia is the best. They have many health benefits to offer apart from weight loss. It has all the essential nutrients, vitamins, and minerals that are essential for your body. While stevia is also known to be the best sugar for weight loss.

    Is glucose-fructose syrup an artificial sweetener? ›

    High-fructose corn syrup (HFCS) is an artificial sugar made from corn syrup. Many experts believe that added sugar and HFCS are key factors in today's obesity epidemic ( 1 , 2 ). HFCS and added sugar are also linked to many other serious health issues, including diabetes and heart disease ( 3 , 4 ).

    Is glucose syrup just sugar? ›

    Glucose syrup is a refined and concentrated solution of dextrose, maltose and higher saccharides, obtained by hydrolysis of starch. It is more distinct than sugar, partly because it is a syrup, which means that the solution is a thick, sweetish liquid.

    Why is glucose syrup in everything? ›

    Glucose syrup is widely used because of its basic properties: its lack of a distinct taste, its transparency and its viscosity. Depending on which type is used, glucose syrups can provide texture, volume, taste, glossiness, improved stability and a longer shelf-life.

    Is glucose syrup high in fructose? ›

    Our analyses of commercial products have shown wide use of fructose-containing glucose syrups. It is true that glucose syrup, rice syrup and wheat syrup may contain high levels of fructose.

    What is a healthy substitute for glucose syrup? ›

    Honey, corn syrup and agave nectar are all good substitutes for glucose syrup. Or you could try inverted sugar syrup, which is made from sucrose instead of glucose. Whatever you choose, make sure to use it in moderation – too much sugar can quickly ruin a dish.

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